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To main content To navigation Link to homepage of CNCR Research Teams Psychiatric & Statistical Genomics Phenotypic modelling in genetics Stem Cell Biology Connectomics Publications People Education Jobs Software & Sumstats News Contact Open menu CNCR / CTG CTG home Complex Trait Genetics lab VU University & VU Medical Centre Amsterdam Center for Neurogenomics and Cognitive Research Neuroscience Campus Amsterdam Go to next slide Go to previous slide Research Research in CTGlab explores the genetic and environmental causes of individual differences in brain-related health and disease. We integrate knowledge from different fields (genetics, neuroscience, bioinformatics, biology, machine learning), use and develop analytical tools to analyze and understand genomic data for complex traits, and connect to neuroscience to prove causation in wet-lab experiments. Research Research in CTGlab explores the genetic and environmental causes of individual differences in brain-related health and disease. We integrate knowledge from different fields (genetics, neuroscience, bioinformatics, biology, machine learning), use and develop analytical tools to analyze and understand genomic data for complex traits, and connect to neuroscience to prove causation in wet-lab experiments. Read more Read more about Research Video’s NWO Brain & Cognition has awarded CTGlab PhD students Anke Hammerschlag and Sabine Mous the first prize for best integrated project and the attractive joint presentation of their collaboration on An Integrative Theory of the Genetically Mediated Neural Substrates of ADHD”. Read more Read more about Video’sCTGlab was setup in 2008 by Danielle Posthuma as a small research group within the CNCR at the VU and the Amsterdam University Medical Centre . Since 2014 CTGlab is a sub-department of the CNCR and Amsterdam-UMC. We participate in Amsterdam Neuroscience . Read more Read more aboutNews A map of chromatin accessibility in the developing human brain A collaboration between Marijn Schipper and Danielle Posthuma from CNCR-CTG and Camiel Mannens and Sten Linnarsson from the Karolinska Institute Sweden has led to the publication of the first map of chromatin accessibility and paired gene expression in the entire developing early embryonic human brain. The study is published May 1, 2024 in Nature. Read more about A map of chromatin accessibility in the developing human brain Neuroscientist Elleke Tissink discovered new genes with widespread effect on brain Neuroscientist Elleke Tissink investigated which genetic factors can influence different characteristics of the brain. With this knowledge, we can better understand why our brains all differ subtly in structure and function. This also provides insight into brain diseases such as ADHD or bipolar disorder. Read more about Neuroscientist Elleke Tissink discovered new genes with widespread effect on brain PoC grant awarded to Sara L. Seoane and Ilan Libedinsky PhD candidates Sara L. Seoane and Ilan Libedinsky, with supervisor Professor Martijn van den Heuvel, have been awarded a Proof of Concept (PoC) grant for €66.000 from Amsterdam Neuroscience for their innovative research on characterizing the evolution of brain aging and its potential link to brain disorders. Read more about PoC grant awarded to Sara L. Seoane and Ilan Libedinsky News Research Statement In the post-GWAS era the aim of genetic research has expanded to the identification of the actual genes underlying stable genetic contributions to various key traits of behavior, cognition and health. Identifying these genes is important as it may lead us to understand why some people are more prone to mental disorders and physical disease than others, and may help improve early diagnosis, prevention and treatment of disease. Research in our lab explores the genetic and environmental causes of individual differences in human traits related to behavior, cognition and mental and physical health. We integrate knowledge from different fields (biology, genetics, neuroimaging, bioinformatics) and use and develop statistical tools to analyze and understand GWAS data for complex traits. Site footer Related sites CNCR INF CTG FGA MCN Contact Brigitte Borgman (management assistant CNCR) Tel: + 31 20 598 71 16 Fax: + 31 20 598 92 81 E-mail: brigitte.borgman@vu.nl Visiting address CNCR, VU University De Boelelaan 1085 1081 HV Amsterdam How to reach us? About this site Disclaimer Privacy Statement All rights reserved © 2024...